Hernan Perez plated the go-ahead run in a five-run sixth inning as the Brewers outslugged the Reds 11-9 in Milwaukee.
Yasmani Grandal drilled a two-run homer to tie the game in the sixth for the Crew, who earned a split of the two-game set. Mike Moustakas and Keston Hiura also went deep in the victory.
Junior Guerra got the win and Joe Hader posted his 12th save.
Tucker Barnhart belted a three-run homer and Derek Dietrich added a solo shot for Cincinnati, which has alternated wins and losses over its last six games.
Wandy Peralta suffered the loss.