Derek Dietrich’s pinch-hit, three-run homer in the seventh inning broke a tie as the Reds dropped the Pirates 5-3 on Opening Day in Cincinnati.
Jose Peraza tied the game earlier in the seventh with a solo shot. Luis Castillo struck out eight over nearly six innings of work and Zach Duke came away with the win.
Pittsburgh starter Jameson Taillon gave up four runs over six-plus frames to get tagged with the loss.
Corey Dickerson homered for the Pirates in defeat and Jung-Ho Kang added a two-run single.